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What's your DNA story? Trace your roots & discover new details about your family history on your mother's side.
• Mitochondrial DNA (mtDNA) sequencing
• Trace your direct maternal lineage
• Access our extensive databases to match your DNA to populations around the world, find long-lost relatives, discover ancient origins & compare against famous people.
• Both men and women can take this test.
Detailed Description:
This DNA test sequences your maternally inherited mitochondrial DNA (mtDNA), allowing you to trace the ancestry of your direct maternal lineage (your mother’s, mother’s, mother’s…maternal lineage).
The mtDNA contains three regions: HVR1, HVR2, and Coding (more information in the genetics section). Testing the HVR1 and HVR2 regions will allow you to make use of all of the search and analysis features of the database. Testing all three regions of the mtDNA is required to confirm your mtDNA haplogroup and subclade.
Choose from the following options:
Upgrade Options: A cost-efficient upgrade option is available. You can start by taking the Standard Test. If this region does not provide a high enough resolution, there is an option to upgrade to the Advanced Test or the Premium Test.
Both males and females have mtDNA, so both genders can take the mtDNA test to trace their maternal ancestry. However, only females will pass their mtDNA down to the next generation.
What is mtDNA?
Mitochondrial DNA (mtDNA) is found in the mitochondria of human cells. Each cell can contain several mitochondria, and each mitochondrion contains dozens of copies of mtDNA. So in every cell there can be thousands of copies of mtDNA. This is different from nuclear DNA, since we only inherit two copies of the autosomal and sex chromosomes per cell.
All of us inherit our mtDNA from only our mothers. This mtDNA essentially remains unchanged through the maternal line, providing an incredibly useful way to trace maternal ancestry.
What is mtDNA Sequencing?
The circular mitochondrial genome has three regions – two small hypervariable (HVR) regions and a large coding region. It is possible to sequence just the HVR1 region, both hypervariable regions (HVR1 and HVR2), or the complete mitochondrial genome (HVR1, HVR2 and the coding region).
The hypervariable regions comprise approximately 1100 bases of the mtDNA genome. Most of the variation in the mtDNA occurs in these regions. If two people have a perfect match at their HVR1 and HVR2 regions, further analysis of the much larger coding region can provide a higher stringency comparison and further resolution. The coding region covers the remainder of the mitochondrial genome, and the complete mitochondrial genome is 16,569 base pairs.
What's Included?
The entire DNA sequences for regions tested are provided to you in your mtDNA test report. Your mtDNA sequencing results are compared to a reference sequence called the “rCRS” (revised Cambridge Reference Sequence), and all of the positions within your mtDNA, which differ from rCRS are listed in your report.
Your unique mtDNA sequence result is known as your mtDNA profile.
Since mtDNA is passed down from mother to child along the direct maternal lineage, people who have descended from the same maternal lineage are expected to have exactly the same or very similar mtDNA profiles.
If two people have different mtDNA profiles, it conclusively confirms that they did not descend from the same maternal lineage.
DNA Reunion Database:
Search for long lost family lines. Ideal for genealogists looking to expand their family tree and confirm or refute family legends, individuals looking for their biological parents and family members separated by adoption or other reasons (e.g. war).
Indigenous DNA Database
Determine which indigenous groups are most similar to your DNA type.
DNA Haplogroups Database:
Trace your ancestry back over 100,000 years to its ancient roots in Africa.
Famous DNA Database:
Compare your DNA to royalty, famous or notable people in history. Profiles include Marie Antoinette, Genghis Khan, Nicholas Copernicus, King Richard III and more.
HOW IT WORKS:
Step 1: Order test kit online
Choose the DNA Maternal Ancestry test. Enjoy the convenience of having the kit delivered straight to your doorstep, eliminating the need for any trips outside your home.
Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Before collecting your sample, make sure to register and activate your test kit online. This step ensures that your sample is correctly processed. Use the painless mouth swab included in your kit, then securely place your sample in the prepaid return envelope provided. Send it back to our laboratory as soon as possible for prompt testing.
Step 3: Receive your results online
Once your sample arrives at the lab, it will be tested with precision and care. Your results will be accessible through the secure online platform, ensuring your personal information remains private and protected. Enjoy peace of mind with the quality guarantee.