Cardiovascular Disease (ApoE) DNA Test

Hyperlipoproteinemia type III is one disease characterized by elevated triglycerides and beta-very low-density lipoproteins. It is associated with an early onset of peripheral vascular disease and CVD.

The APOE gene is a major genetic risk factor involved in CVD. It can also influence how well you will respond to dietary changes and blood pressure lowering medications to control your cholesterol levels. A simple mouth swab is all we need to determine your APOE genotype.

The Genetics

The APOE gene is a major genetic risk factor involved in cardiovascular disease. It encodes Apolipoprotein E (ApoE), a protein involved in the production, delivery, and utilization of cholesterol in the body.

Different Versions Of The APOE Gene:

There are several different versions or alleles of APOE. The three most common alleles are known as e2, e3 and e4. Each of these alleles produces a slightly different version of the ApoE protein.

• e3: The most common, neutral allele. No increased or decreased risk of cardiovascular disease
• e4: Associated with an increased risk of high LDL-cholesterol levels and atherosclerosis
• e2: Associated with lower LDL-cholesterol levels in the blood, but increased risk of high blood sugar and hyperlipoproteinemia type III, leading to a higher risk of cardiovascular disease

 How Does Your APOE Genotype Influence Your Risk of Cardiovascular Disease?

•  Two copies of the e3 allele:  Not at increased risk of CVD
•  One e3 allele and one e2 allele: Not at increased risk of CVD
•  Two copies of the e2 allele: Lower LDL-cholesterol but increased risk of hyperlipoproteinemia type III, which can contribute towards CVD
•  One or two copies of the e4 allele: Elevated LDL-cholesterol and increased risk of CVD.

 How It Works:

Step 1: Order test kit online
Choose the cardiovascular disease (ApoE) DNA test. Enjoy the convenience of having the kit delivered straight to your doorstep, eliminating the need for any trips outside your home.

Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Before collecting your sample, make sure to register and activate your test kit online. This step ensures that your sample is correctly processed. Use the painless mouth swab included in your kit, then securely place your sample in the prepaid return envelope provided. Send it back to our laboratory as soon as possible for prompt testing.

Step 3: Receive your results online
Once your sample arrives at the lab, it will be tested with precision and care. Your results will be accessible through the secure online platform, ensuring your personal information remains private and protected. Enjoy peace of mind with the quality guarantee.