Thrombotic Risk DNA Test

The Genetics

Genetic changes in three genes are analyzed in this thrombotic risk test. Each change contributes to an increased risk of thrombosis

VARIANTS TESTED:

• F5 – the Factor V Leiden mutation (1691G>A)
• F2 – the prothrombin mutation (20210G>A)
• MTHFR – two mutations (677C>T and 1298A>C)

We inherit two copies of each gene – one from each parent. Therefore we can inherit two normal copies of a gene (homozygous normal), two copies that carry a genetic mutation (homozygous mutant), or one normal copy and one mutated copy (heterozygous). This means that we can inherit several different combinations of the F5, F2 and MTHFR genes. Each combination is associated with a different risk of thrombophilia.

 REDUCING YOUR RISK OF A BLOOD CLOT:

• Maintain a healthy body weight
• Follow a healthy diet
• Increase your blood flow with exercise
• Avoid extended periods of immobility
• Avoid smoking
• Reduce homocysteine levels by getting plenty of folate and other B vitamins
• Wear compression stocking on long flights
• If your risk is very high, seek medical treatment (e.g. anticoagulants)

 How It Works

Step 1: Order test kit online
Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Step 3: Receive your results online

NOTE: Please provide your email address for reporting results.